95071-7

LOINC 2.82

Chromosome region 14q32 rearrangements in Bone marrow by FISH

Chr 14q32 Rearr Mar FISH

Definition

  • This tests detects 14q32 rearrangements by fluorescence in situ hybridization (FISH) in patients with multiple myeloma, a white blood cell cancer that affects plasma cells. Four common 14q32 translocations involving the IGH gene include CCND1/t(11;14), FGFR3/t(4;14), MAF/t(14;16) and MAFB/t(14;20).

Component

  • Chromosome region 14q32 rearrangements

Specimen / system

  • Bone mar

Class

  • MOLPATH.REARRANGE

Property

  • Find

Scale

  • Doc

Method

  • FISH

Related names

  • BM; BON; Bone marrow; Chr 14q32 Rearr; Chromosom; Chromosomes; Cyto loc; Document; Finding; Findings; Fluorescent in situ hybridization; Genetics; Heredity; Heritable; IGH gene; IGH gene rearrangements; Inherited; MAR; Marrow (bone); minimal angle of resolution; Minimum angle of resolution; Molecular pathology; MOLPATH; MOLPATH.REARRANGEMENTS; Multiple myeloma; Plasma cell myeloma; Point in time; Random; Rearr; Rearrangement

Index terms

  • BM
  • BON
  • Bone marrow
  • Chr 14q32 Rearr
  • Chromosom
  • Chromosomes
  • Cyto loc
  • Document
  • Finding
  • Findings
  • Fluorescent in situ hybridization
  • Genetics
  • Heredity
  • Heritable
  • IGH gene
  • IGH gene rearrangements
  • Inherited
  • MAR
  • Marrow (bone)
  • minimal angle of resolution
  • Minimum angle of resolution
  • Molecular pathology
  • MOLPATH
  • MOLPATH.REARRANGEMENTS
  • Multiple myeloma
  • Plasma cell myeloma
  • Point in time
  • Random
  • Rearr
  • Rearrangement