SARS-CoV-2 (COVID-19) neutralizing antibody [Presence] in Serum by pVNT

SARS-CoV-2 NAb Ser Ql pVNT

Definition

Qualitative results for SARS Coronavirus 2 (SARS-CoV-2) virus neutralizing antibodies in serum by pVNT (pseudovirus neutralization test). Neutralizing antibody testing is performed to determine whether the antibodies produced after SARS-CoV-2 infection or in response to a vaccination are able to neutralize the virus and prevent infection or re-infection. Different methods can be used to determine the presence of neutralizing antibodies, including VNT (virus neutralization test) and pVNT, which are represented in LOINC as the Method "Neutralization" and "pVNT", respectively. The pVNT method for SARS-CoV-2 neutralizing antibody testing uses recombinant pseudoviruses that incorporate the S protein from SARS-CoV-2, whereas VNT uses SARS-CoV-2 virus from a clinical isolate or recombinant SARS-CoV-2 expressing reporter proteins.

2019 Novel Coronavirus; 2019-nCoV; ABS; Aby; Antby; Anti; Antibodies; Antibody; Autoantibodies; Autoantibody; Corona virus; COVID19; COVID-19; ID; II; Infectious Disease; InfectiousDisease; Microbiology; NAb; Ordinal; Point in time; PR; QL; Qual; Qualitative; Random; SARS Coronavirus 1; SARS-CoV; SARS-CoV-1; SARS-CoV-2; SARS-CoV-2 Nab; Screen; Serum; Severe Acute Respiratory Syndrome; SR; Viral Pneumonias; Wuhan coronavirus