96981-6

LOINC 2.82

Trisomy 13, trisomy 18 or triploidy risk [Likelihood] in Plasma cell-free+WBC DNA by calculation

T13+T18+Trip risk WBC.DNA+cfDNA Calc

Definition

  • The combined fetal trisomy 13+trisomy 18+triploidy risk value is calculated in cases where the SNP-based noninvasive prenatal test did not return a result due to low fetal fraction (FF) or the inability to make a high-confidence call. FF is known to be lower in cases of trisomy 13, trisomy 18 and digynic (maternal) triploidy, but not all cases of low FF is due to aneuploidy. Combined risk calculations may include the FF value, gestational age (GA), maternal weight (MW) and prior risk data to determine the overall risk. [PMID: 30014528]

Component

  • Fetal trisomy 13+trisomy 18+triploidy risk

Specimen / system

  • WBC.DNA+Plas.cfDNA

Class

  • MOLPATH

Property

  • Likelihood

Scale

  • Qn

Method

  • Calculated

Related names

  • Calc; Calculation; Edward syndrome; Gyn; Gynecology; Leukocytes; Molecular pathology; MOLPATH; OB; ObGyn; Obstetrics; Pl; Plasma; Plsm; Point in time; QNT; Quan; Quant; Quantitative; Random; Risk; T13+T18+Trip risk; Ts; WBC.DNA+cfDNA; WBCs; White blood cells

Index terms

  • Calc
  • Calculation
  • Edward syndrome
  • Fetal trisomy 13+trisomy 18+triploidy risk
  • Gyn
  • Gynecology
  • Leukocytes
  • Molecular pathology
  • MOLPATH
  • OB
  • ObGyn
  • Obstetrics
  • Pl
  • Plasma
  • Plsm
  • Point in time
  • QNT
  • Quan
  • Quant
  • Quantitative
  • Random
  • Risk
  • T13+T18+Trip risk
  • Ts
  • WBC.DNA+cfDNA
  • WBCs
  • White blood cells