97760-3

LOINC 2.82

MLH1 gene methylation analysis in Blood by Molecular genetics method

MLH1 Methyl Anl Bld

Definition

  • MLH1 gene methylation analysis in blood is performed as an adjunct to positive hypermethylation in tumor to distinguish between somatic and germline hypermethylation, or as an adjunct to negative MLH1 germline testing in cases where colon or endometrial tumor demonstrates microsatellite instability-H (MSI-H) and loss of MLH1 protein expression.

Component

  • MLH1 gene methylation analysis

Specimen / system

  • Bld

Class

  • MOLPATH

Property

  • Find

Scale

  • Doc

Method

  • Molgen

Related names

  • Blood; COCA2; DNA methylation; Document; FCC2; Finding; Findings; hMLH1; HNPCC; HNPCC2; Lynch syndrome; MGC5172; MLH1 Methyl Anl; Molecular genetics; Molecular pathology; MOLPATH; mutL homolog 1; MutL homolog 1, colon cancer, nonpolyposis type 2; PCR; Point in time; Random; WB; Whole blood

Index terms

  • Blood
  • COCA2
  • DNA methylation
  • Document
  • FCC2
  • Finding
  • Findings
  • hMLH1
  • HNPCC
  • HNPCC2
  • Lynch syndrome
  • MGC5172
  • MLH1 Methyl Anl
  • Molecular genetics
  • Molecular pathology
  • MOLPATH
  • mutL homolog 1
  • MutL homolog 1, colon cancer, nonpolyposis type 2
  • PCR
  • Point in time
  • Random
  • WB
  • Whole blood