97761-1

LOINC 2.82

MLH1 gene methylation analysis in Tumor by Molecular genetics method

MLH1 Methyl Anl Tumor

Definition

  • MLH1 gene methylation analysis in tumor is an adjunct test when tumor (colon or endometrial) demonstrates microsatellite instability (MSI-H) and loss of MLH1 protein expression, to help distinguish a somatic versus germline event.

Component

  • MLH1 gene methylation analysis

Specimen / system

  • Tumor

Class

  • MOLPATH

Property

  • Find

Scale

  • Doc

Method

  • Molgen

Related names

  • Cancer; COCA2; DNA methylation; Document; FCC2; Finding; Findings; hMLH1; HNPCC; HNPCC2; Lynch syndrome; MGC5172; MLH1 Methyl Anl; Molecular genetics; Molecular pathology; MOLPATH; mutL homolog 1; MutL homolog 1, colon cancer, nonpolyposis type 2; PCR; Point in time; Random; tumors; tumour; tumours

Index terms

  • Cancer
  • COCA2
  • DNA methylation
  • Document
  • FCC2
  • Finding
  • Findings
  • hMLH1
  • HNPCC
  • HNPCC2
  • Lynch syndrome
  • MGC5172
  • MLH1 Methyl Anl
  • Molecular genetics
  • Molecular pathology
  • MOLPATH
  • mutL homolog 1
  • MutL homolog 1, colon cancer, nonpolyposis type 2
  • PCR
  • Point in time
  • Random
  • tumors
  • tumour
  • tumours