97913-8

LOINC 2.82

Thrombin peak [Molar amount] in Platelet poor plasma by Chromogenic method --after addition of factor VIII Ab

Thrombin peak p FVIII Ab sub PPP Qn Chro

Definition

  • The peak thrombin is the maximum thrombin measurement during a thrombin generation test. Decreased peak thrombin is associated with bleeding tendencies, while increased peak thrombin is associated with thrombosis. [PMID: 21262433] If the peak is significantly decreased in the presence of Factor VIII antibodies, that indicates that Factor VIII had a significant contribution to the baseline thrombin peak (measured without Factor VIII antibodies). [PMID: 12871369]

Component

  • Thrombin peak^after addition of Factor VIII Ab

Specimen / system

  • PPP

Class

  • COAG

Property

  • Sub

Scale

  • Qn

Method

  • Chromo

Related names

  • Chromogenic assay; COAGULATION; ENZY; Enzymatic assay; F8; Fac; Fact; Fact VIII; Factor 8; FVIII; Hematology; Heme; p FVIII Ab; Plas; Platelet poor plasma; Point in time; QNT; Quan; Quant; Quantitative; Random; Substance amount; Throm

Index terms

  • Chromogenic assay
  • COAGULATION
  • ENZY
  • Enzymatic assay
  • F8
  • Fac
  • Fact
  • Fact VIII
  • Factor 8
  • FVIII
  • Hematology
  • Heme
  • p FVIII Ab
  • Plas
  • Platelet poor plasma
  • Point in time
  • QNT
  • Quan
  • Quant
  • Quantitative
  • Random
  • Substance amount
  • Throm
  • Thrombin peak^after addition of Factor VIII Ab