98122-5

LOINC 2.82

Neutrophil.fMLP and PMA stimulated DHR panel by Flow cytometry (FC)

Neut fMLP + PMA stim DHR Pnl Patient FC

Definition

  • The phorbol myristate acetate (PMA) and N-formyl-methionyl-leucyl-phenylalanine (fMLP) stimulated neutrophil dihydrorhodamine (DHR) test assesses neutrophil activation and NADPH oxidase function when stimulated by PMA and fMLP (different populations of neutrophils are stimulated by PMA and fMLP, respectively). This test is used to diagnose chronic granulomatous disease (CGD) and complete myeloperoxidase deficiency; monitor chimerism and NADPH oxidase function after stem cell transplant, assess NADPH oxidase activity prior to transplant; identify and monitor chromosome X inactivation changes with age in carrier females with X-linked CGD; and diagnose Rac2 deficiency. To report results for the fMLP stimulated neutrophil DHR test alone, use [LOINC: 98123-3]. To report results for the PMA stimulated neutrophil DHR test alone, use [LOINC: 98124-1].

Component

  • Neutrophil.fMLP & PMA stimulated DHR panel

Specimen / system

  • ^Patient

Class

  • PANEL.HEM/BC

Property

  • -

Scale

  • -

Method

  • Flow cytometry

Related names

  • Dynamic; FC; HEMATOLOGY/CELL COUNTS; Neut; Neut fMLP + PMA stim DHR Pnl; Neutr; Neutrophils; Pan; PANEL.HEMATOLOGY& CELL COUNTS; Panl; PMN; Pnl; PNM; Point in time; Random

Index terms

  • Dynamic
  • FC
  • HEMATOLOGY/CELL COUNTS
  • Neut
  • Neut fMLP + PMA stim DHR Pnl
  • Neutr
  • Neutrophil.fMLP & PMA stimulated DHR panel
  • Neutrophils
  • Pan
  • PANEL.HEMATOLOGY& CELL COUNTS
  • Panl
  • PMN
  • Pnl
  • PNM
  • Point in time
  • Random