99971-4

LOINC 2.82

Hemophagocytic lymphohistiocytosis multigene analysis in Blood or Tissue by Molecular genetics method

HLH multigene analysis Bld/T

Definition

  • Multigene analysis for hemophagocytic lymphohistiocytosis (HLH), a syndrome characterized by hyperactivation of the immune system, excessive cytokine secretion and severe systemic inflammation. HLH is classified as familial (FHL) when associated with mutations in specific genes, such as PRF1, UNC13D, STX11, and STXBP2 genes.[PMID: 33746956] Testing is performed for diagnostic, prognostic, and therapeutic assessment in patients with HLH.

Component

  • Hemophagocytic lymphohistiocytosis multigene analysis

Specimen / system

  • Bld/Tiss

Class

  • MOLPATH

Property

  • Find

Scale

  • Doc

Method

  • Molgen

Related names

  • Blood; Document; Finding; Findings; Gene; Gene panel; HLH multigene analysis; Molecular genetics; Molecular pathology; MOLPATH; Multi-gene study; Multiple-gene panel test; PCR; Point in time; Random; Tissue; Tissue, unspecified; WB; Whole blood; Whole blood or Tissue

Index terms

  • Blood
  • Document
  • Finding
  • Findings
  • Gene
  • Gene panel
  • HLH multigene analysis
  • Molecular genetics
  • Molecular pathology
  • MOLPATH
  • Multi-gene study
  • Multiple-gene panel test
  • PCR
  • Point in time
  • Random
  • Tissue
  • Tissue, unspecified
  • WB
  • Whole blood
  • Whole blood or Tissue