2A20.1

ICD-11 MMS 2026-01

Chronic neutrophilic leukaemia

Description

A rare chronic myeloproliferative neoplasm characterised by sustained peripheral blood neutrophilia, bone marrow hypercellularity due to neutrophilic granulocyte proliferation, and hepatosplenomegaly. The neutrophils lack dysplasia and often show toxic granulations. There is no detectable Philadelphia chromosome or BCR/ABL1 fusion gene.

Index terms

  • Chronic neutrophilic leukaemia

Exclusions from above levels

  • 2E03 – Malignant neoplasm metastasis in bone or bone marrow
  • http://id.who.int/icd/entity/501778925 – Malignant neoplasm metastasis in lymph nodes
  • http://id.who.int/icd/entity/97145147 – Malignant neoplasm metastasis in thymus gland

Sibling codes

  • 2A20.0 – Chronic myelogenous leukaemia, BCR-ABL1-positive
  • 2A20.2 – Primary myelofibrosis
  • 2A20.3 – Chronic eosinophilic leukaemia, not elsewhere classified
  • 2A20.4 – Polycythaemia vera
  • 2A20.5 – Non mast cell myeloproliferative neoplasm, unclassifiable
  • 2A20.Y – Other specified non mast cell myeloproliferative neoplasms
  • 2A20.Z – Non mast cell myeloproliferative neoplasms, unspecified

Foundation entity

Chronic neutrophilic leukaemia – http://id.who.int/icd/entity/426734182

Allowed postcoordination axes

Part of: 2A20: Non mast cell myeloproliferative neoplasms › 02: Neoplasms