2A51

ICD-11 MMS 2026-01

Myeloid neoplasm associated with PDGFRB rearrangement

Description

A distinct type of myeloid neoplasm that occurs in association with rearrangement of PDGFRB gene at 5q32. Patients usually present with a picture resembling chronic myelomonocytic leukaemia and, less often, atypical chronic myeloid leukaemia or chronic eosinophilic leukaemia.

Index terms

  • Myeloid neoplasm associated with PDGFRB rearrangement
  • Chronic myelomonocytic leukaemia with eosinophilia associated with t(5;12)
  • Myeloid neoplasms associated with PDGFRB rearrangement
Show allHide
  • Myeloid neoplasms with PDGFRB rearrangement

Exclusions from above levels

  • 2E03 – Malignant neoplasm metastasis in bone or bone marrow
  • http://id.who.int/icd/entity/501778925 – Malignant neoplasm metastasis in lymph nodes
  • http://id.who.int/icd/entity/97145147 – Malignant neoplasm metastasis in thymus gland

Sibling codes

  • 2A50 – Myeloid or lymphoid neoplasm associated with PDGFRA rearrangement
  • 2A52 – Myeloid or lymphoid neoplasms with FGFR1 abnormalities
  • 2A5Z – Myeloid or lymphoid neoplasms with eosinophilia and abnormalities of PDGFRA, PDGFRB or FGFR1, unspecified

Foundation entity

Myeloid neoplasm associated with PDGFRB rearrangement – http://id.who.int/icd/entity/625932159

Allowed postcoordination axes

Part of: 02: Neoplasms