Myeloid or lymphoid neoplasms with FGFR1 abnormalities

Description

Hematologic neoplasms characterised by the rearrangement of the FGFR1 gene, resulting in translocations with an 8p11 breakpoint. Patients may present with a myeloproliferative neoplasm, acute myeloid leukaemia, lymphoblastic lymphoma/leukaemia of T or B-cell lineage, or acute leukaemia of mixed phenotype.

Index terms

Myeloid or lymphoid neoplasms with FGFR1 abnormalities

Exclusions from above levels

2E03 – Malignant neoplasm metastasis in bone or bone marrow
http://id.who.int/icd/entity/501778925 – Malignant neoplasm metastasis in lymph nodes
http://id.who.int/icd/entity/97145147 – Malignant neoplasm metastasis in thymus gland

Sibling codes

2A50 – Myeloid or lymphoid neoplasm associated with PDGFRA rearrangement
2A51 – Myeloid neoplasm associated with PDGFRB rearrangement
2A5Z – Myeloid or lymphoid neoplasms with eosinophilia and abnormalities of PDGFRA, PDGFRB or FGFR1, unspecified

Foundation entity

Myeloid or lymphoid neoplasms with FGFR1 abnormalities – http://id.who.int/icd/entity/2019647878

Allowed postcoordination axes

hasManifestation

Part of: 02: Neoplasms