2A60.1

ICD-11 MMS 2026-01

Acute myeloid leukaemia with myelodysplasia-related changes

Description

An acute myeloid leukaemia with at least 20% blasts in the bone marrow or blood, and either a previous history of myelodysplastic syndrome, multilineage dysplasia or typical myelodysplastic syndrome-related cytogenetic abnormalities. There is no history of prior cytotoxic therapy for an unrelated disorder, and there is absence of the genetic abnormalities that are present in acute myeloid leukaemia with recurrent genetic abnormalities.

Index terms

  • Acute myeloid leukaemia with myelodysplasia-related changes
  • Acute myeloblastic leukaemia with multilineage dysplasia
  • Acute myeloid leukaemia with myelodysplasia-related features
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  • acute myeloid leukaemia with multilineage dysplasia without mention of remission
  • Acute myeloid leukaemia with multilineage dysplasia in complete remission

Exclusions from above levels

  • 2E03 – Malignant neoplasm metastasis in bone or bone marrow
  • http://id.who.int/icd/entity/501778925 – Malignant neoplasm metastasis in lymph nodes
  • http://id.who.int/icd/entity/97145147 – Malignant neoplasm metastasis in thymus gland

Sibling codes

  • 2A60.0 – Acute myeloid leukaemia with recurrent genetic abnormalities
  • 2A60.2 – Therapy-related myeloid neoplasms
  • 2A60.3 – Acute myeloid leukaemia, not elsewhere classified by criteria of other types
  • 2A60.4 – Myeloid proliferation associated with Down syndrome
  • 2A60.5 – Blastic plasmacytoid dendritic cell neoplasm
  • 2A60.Y – Other specified acute myeloid leukaemias and related precursor neoplasms
  • 2A60.Z – Acute myeloid leukaemias and related precursor neoplasms, unspecified

Foundation entity

Acute myeloid leukaemia with myelodysplasia-related changes – http://id.who.int/icd/entity/1235412948

Allowed postcoordination axes

Part of: 2A60: Acute myeloid leukaemias and related precursor neoplasms › 02: Neoplasms