Light and heavy chain deposition disease

Description

A disease of the kidney, caused by proliferation and deposition of pieces of truncated or abnormal light and heavy chain segments of white blood cells. This disease is characterised by fibrillar or granular tissue deposits and renal dysfunction, which may lead to organ failure. Confirmation is by identification of light and heavy chain deposition tissue biopsy under a microscope.

Exclusions from above levels

• 2E03 – Malignant neoplasm metastasis in bone or bone marrow
• http://id.who.int/icd/entity/501778925 – Malignant neoplasm metastasis in lymph nodes
• http://id.who.int/icd/entity/97145147 – Malignant neoplasm metastasis in thymus gland