Immunodeficiency-associated lymphoproliferative disorders

Description

Post-transplant lymphoproliferative disorder (PTLD) is a polyclonal (benign) or clonal (malignant) proliferation of lymphoid cells that develops as a consequence of immunosuppression in a recipient of a solid organ or bone marrow allograft. PTLDs comprise a spectrum ranging from early, Epstein-Barr virus (EBV)-driven polyclonal lymphoid proliferations to EBV-positive or EBV-negative lymphomas of predominantly B-cell or less often T-cell type. In other immunodeficiency-associated lymphoproliferative disorders, association with EBV is less pronounced.

Inclusions

PTLD - [Post transplant lymphoproliferative disorder]

Exclusions from above levels

2E03 – Malignant neoplasm metastasis in bone or bone marrow
http://id.who.int/icd/entity/501778925 – Malignant neoplasm metastasis in lymph nodes
http://id.who.int/icd/entity/97145147 – Malignant neoplasm metastasis in thymus gland

Child codes

2B32.0 – Post-transplant lymphoproliferative disorder, early lesion
2B32.1 – Reactive plasmacytic hyperplasia
2B32.2 – Post-transplant lymphoproliferative disorder, Infectious mononucleosis-like
2B32.3 – Polymorphic post-transplant lymphoproliferative disorder
2B32.Y – Other specified immunodeficiency-associated lymphoproliferative disorders
2B32.Z – Immunodeficiency-associated lymphoproliferative disorders, unspecified

Sibling codes

2A60 – Acute myeloid leukaemias and related precursor neoplasms
2A61 – Acute leukaemias of ambiguous lineage
2B30 – Hodgkin lymphoma
2B31 – Histiocytic or dendritic cell neoplasms
2B33 – Malignant haematopoietic neoplasms without further specification
2B3Z – Neoplasms of haematopoietic or lymphoid tissues, unspecified

Foundation entity

Immunodeficiency-associated lymphoproliferative disorders – http://id.who.int/icd/entity/1678636940

Allowed postcoordination axes

Part of: 02: Neoplasms