2C12.01

ICD-11 MMS 2026-01

Hepatoblastoma

Description

A malignant liver neoplasm that occurs almost exclusively in infants, although isolated cases in older children and adults have been reported. Grossly, hepatoblastoma is solid, well circumscribed, and more often solitary than multiple. Microscopically, most of the tumours are composed exclusively of immature hepatocytic elements. About a fourth of hepatoblastomas contain a stromal component that may be undifferentiated or develop into bone or cartilage.

Coding note from above levels

For use of this category, reference should be made to the mortality coding rules and guidelines in the Reference Guide.

Index terms

  • Hepatoblastoma

Exclusions from above levels

  • 2C17 – Malignant neoplasm of biliary tract NOS
  • 2D80 – Secondary malignant neoplasm of liver
  • http://id.who.int/icd/entity/111033337 – Malignant neoplasm metastasis in digestive system
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  • http://id.who.int/icd/entity/1965082709 – Malignant mesenchymal neoplasms
  • http://id.who.int/icd/entity/794095161 – Malignant neoplasms of lip, oral cavity or pharynx
  • http://id.who.int/icd/entity/879154182 – Neoplasms of central nervous system or related structures
  • http://id.who.int/icd/entity/944754984 – Neoplasms of haematopoietic or lymphoid tissues

Sibling codes

  • 2C12.00 – Combined hepatocellular-cholangiocarcinoma
  • 2C12.02 – Hepatocellular carcinoma of liver
  • 2C12.03 – Mesothelial carcinoma of liver
  • 2C12.0Y – Other specified malignant neoplasm of liver
  • 2C12.0Z – Malignant neoplasm of liver, unspecified

Foundation entity

Hepatoblastoma – http://id.who.int/icd/entity/1556608523

Allowed postcoordination axes

Part of: 2C12.0: Malignant neoplasm of liver › 2C12: Malignant neoplasms of liver or intrahepatic bile ducts › 02: Neoplasms