2C12.10

ICD-11 MMS 2026-01

Intrahepatic cholangiocarcinoma

Description

A carcinoma that arises from the intrahepatic bile duct epithelium in any site of the intrahepatic biliary tree. Grossly, the malignant lesions are solid, nodular, and grayish. Morphologically, the vast majority of cases are adenocarcinomas. Early detection is difficult and the prognosis is generally poor.

Coding note from above levels

For use of this category, reference should be made to the mortality coding rules and guidelines in the Reference Guide.

Index terms

  • Intrahepatic cholangiocarcinoma
  • Adenocarcinoma of intra-hepatic bile ducts
  • Adenocarcinoma, bile duct type of liver (deprecated)
Show allHide
  • Bile duct carcinoma of liver
  • Cholangiocarcinoma of liver
  • Cholangiocarcinoma, unspecified site

Exclusions from above levels

  • 2C17 – Malignant neoplasm of biliary tract NOS
  • 2D80 – Secondary malignant neoplasm of liver
  • http://id.who.int/icd/entity/111033337 – Malignant neoplasm metastasis in digestive system
Show allHide
  • http://id.who.int/icd/entity/1965082709 – Malignant mesenchymal neoplasms
  • http://id.who.int/icd/entity/794095161 – Malignant neoplasms of lip, oral cavity or pharynx
  • http://id.who.int/icd/entity/879154182 – Neoplasms of central nervous system or related structures
  • http://id.who.int/icd/entity/944754984 – Neoplasms of haematopoietic or lymphoid tissues

Sibling codes

  • 2C12.1Y – Other specified malignant neoplasms of intrahepatic bile ducts
  • 2C12.1Z – Malignant neoplasm of intrahepatic bile ducts, unspecified

Foundation entity

Intrahepatic cholangiocarcinoma – http://id.who.int/icd/entity/1253728223

Allowed postcoordination axes

Part of: 2C12.1: Malignant neoplasm of intrahepatic bile ducts › 2C12: Malignant neoplasms of liver or intrahepatic bile ducts › 02: Neoplasms