Systemic lupus erythematosus

Description

Systemic lupus erythematosus (SLE) is a clinically multisystem disease, which is autoimmune in origin and is characterised by the presence of autoantibodies directed against nuclear antigens. Manifestations include rash, arthritis and fatigue, nephritis, neurological problems, anaemia and thrombocytopenia at the more severe end of the spectrum.

Exclusions from above levels

• 02 – Neoplasms
• 18 – Complications of pregnancy, childbirth and the puerperium
• 20 – Developmental anomalies