5A61.0

ICD-11 MMS 2026-01

Hypopituitarism

Description

A disorder manifesting a deficiency or decrease of one or more pituitary hormones, which is caused by a variety of diseases such as tumour, trauma/surgery, irradiation, inflammation and haemorrhage/infarction.

Index terms

  • Hypopituitarism
  • anterior pituitary hypofunction
  • anterior pituitary insufficiency (in part)
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  • deficient secretion of all pituitary hormones
  • deficient secretion of one or more pituitary hormones
  • hypohypophysism
  • hypophyseal dwarfism
  • hypophyseal dystrophy
  • hypophyseal short stature
  • hypopituitarism syndrome
  • hypopituitary cachexia
  • hypopituitary dwarfism
  • hyposomatotropic dwarfism
  • juvenile hypopituitarism
  • panhypopituitarism syndrome
  • pituitary cachexia
  • pituitary deficiency
  • pituitary dwarfism
  • pituitary failure
  • pituitary gland hypofunction
  • pituitary hypoadrenocorticism
  • pituitary hypofunction
  • pituitary hypogonadism
  • pituitary infantilism
  • pituitary insufficiency NOS
  • pituitary short stature
  • postpartum hypopituitarism
  • postpartum panhypopituitary syndrome
  • prepubertal dwarfism
  • prepubertal panhypopituitarism
  • primary hypopituitarism
  • secondary hypogonadism
  • subpituitarism
  • Nonacquired hypopituitarism
  • Non-acquired pituitary deficiency
  • Isolated FSH deficiency
  • Isolated follicle stimulating hormone deficiency
  • Nonacquired combined hypopituitarism
  • Adenohypophysis deficiency with or without pituitary stalk interruption syndrome (PSIS)
  • Non-acquired combined pituitary deficiency
  • Panhypopituitarism
  • Septo-optic dysplasia
  • De Morsier syndrome
  • SOD - [Septo-optic dysplasia]
  • Septooptic dysplasia spectrum
  • septo-optic dysplasia sequence
  • Nonacquired isolated growth hormone deficiency
  • Congenital IGHD - [isolated growth hormone deficiency]
  • Congenital isolated growth hormone deficiency
  • Pituitary nanism
  • Growth hormone deficiency with or without pituitary stalk interruption syndrome
  • Growth hormone deficiency with or without PSIS - [pituitary stalk interruption syndrome]
  • Genetic growth hormone deficiency
  • X-linked intellectual deficit with isolated growth hormone deficiency
  • Idiopathic growth hormone deficiency
  • growth hormone insufficiency
  • isolated deficiency of [HGH] - human growth hormone
  • isolated deficiency of growth hormone
  • isolated growth hormone insufficiency
  • Short stature due to growth hormone qualitative anomaly
  • Kowarski syndrome
  • Nanism due to growth hormone qualitative anomaly
  • Pituitary stalk interruption syndrome
  • Ectopic neurohypophysis
  • PSIS - [pituitary stalk interruption syndrome]
  • Short stature due to a defect in growth hormone receptor or post receptor pathway
  • GHIS - [Growth hormone insensitivity syndrome]
  • Growth hormone insensitivity syndrome
  • Growth delay due to insulin-like growth factor I deficiency
  • Growth delay - deafness- intellectual deficit
  • IGF-1 - [ insulin-like growth factor I] deficiency
  • Primary insulin-like growth factor deficiency
  • Growth delay due to insulin-like growth factor I resistance
  • Resistance to IGF-1 - [ insulin-like growth factor I]
  • Short stature due to growth hormone resistance
  • Complete growth hormone insensitivity
  • Growth hormone receptor deficiency
  • Laron syndrome
  • Laron-type dwarfism
  • Primary GH resistance
  • Primary growth hormone insensitivity
  • Primary growth hormone resistance
  • Short stature due to primary acid-labile subunit deficiency
  • Laron syndrome with immunodeficiency
  • Congenital hypogonadotropic hypogonadism
  • Anosmic congenital hypogonadotropic hypogonadism
  • Congenital hypogonadotropic hypogonadism with anosmia
  • Kallmann syndrome
  • anosmia eunuchoidism
  • dysplasia olfactogenitalis of de Morsier
  • gonadotrophin deficiency with anosmia
  • hypogonadotropic eunuchoidism
  • Normosmic congenital hypogonadotropic hypogonadism
  • Isolated congenital gonadotropin deficiency
  • isolated gonadotrophin deficiency
  • Syndrome with hypogonadotropic hypogonadism
  • Bardet-Biedl syndrome
  • BBS - [Bardet-Biedl syndrome]
  • Cataract - intellectual deficit - hypogonadism
  • CHARGE syndrome
  • CHARGE association
  • Choanal atresia, Coloboma, Characteristic ears and Cranial nerve anomalies
  • Coloboma, Heart defect, Atresia choanae, Retarded growth and development, Genital hypoplasia, Ear anomalies/deafness
  • Woodhouse-Sakati syndrome
  • Diabetes - hypogonadism - deafness - intellectual deficit
  • WSS - [Woodhouse-Sakati syndrome]
  • Hypogonadotropic hypogonadism associated with other endocrinopathies
  • Acquired hypopituitarism
  • Secondary hypopituitarism
  • Drug-induced hypopituitarism
  • drug hypopituitarism
  • medicament-induced hypopituitarism
  • Tumoural hypopituitarism
  • Infectious hypopituitarism
  • Autoimmune hypopituitarism
  • Vascular hypopituitarism
  • Sheehan syndrome
  • Sheehan disease
  • Hypopituitarism due to a metabolic disease
  • Hypopituitarism secondary to a metabolic disease
  • Hypopituitarism due to a granulomatous disease
  • Hypopituitarism secondary to a granulomatous disease
  • Traumatic hypopituitarism
  • Hypophysitis
  • Lymphocytic hypophysitis
  • Granulomatous hypophysitis
  • IgG4-related hypophysitis
  • Xanthomatous hypophysitis
  • Pineal germinoma
  • Suprasellar germinoma
  • Pituitary deficiency due to Rathke pouch cysts
  • Pituitary dermoid or epidermoid cysts
  • Pituitary deficiency due to empty sella turcica syndrome
  • Pituitary apoplexy
  • Late-onset isolated ACTH deficiency
  • Late-onset isolated adrenocorticotropin deficiency
  • Idiopathic hypopituitarism
  • Simmonds Syndrome
  • Amenorrhoea-hyperprolactinaemia syndrome
  • Brissaud's infantilism or dwarfism
  • Female infertility associated with pituitary-hypothalamic origin
  • Fertile eunuch syndrome
  • Infantilism syndrome
  • Ischaemic pituitary necrosis
  • Ischaemic postpartum pituitary necrosis
  • Isolated deficiency of pituitary hormone
  • pituitary hormone deficiency
  • Isolated lutropin deficiency
  • Isolated luteinising hormone deficiency
  • Isolated somatotropin deficiency
  • somatotropin deficiency
  • Lorain dwarfism
  • Lorain infantilism
  • Lorain-Levi dwarfism
  • Necrosis of pituitary gland
  • Postpartum pituitary necrosis
  • postpartum necrosis of pituitary gland
  • Myopathy in hypopituitarism
  • Olfactogenital dysplasia

Inclusions

  • pituitary cachexia
  • pituitary short stature

Exclusions from above levels

  • 2A00 – Craniopharyngioma
  • 5D43 – Postprocedural hypopituitarism
  • 18 – Pregnancy, childbirth or the puerperium
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  • http://id.who.int/icd/entity/1004987305 – Transitory endocrine or metabolic disorders specific to fetus or newborn

Foundation children elsewhere

  • LD90.3 – Prader-Willi syndrome

Sibling codes

  • 5A61.1 – Adrenocorticotropic hormone deficiency
  • 5A61.2 – Gonadotropin deficiency
  • 5A61.3 – Growth hormone deficiency
  • 5A61.4 – Thyroid stimulating hormone deficiency
  • 5A61.5 – Central diabetes insipidus
  • 5A61.6 – Oxytocin deficiency
  • 5A61.Y – Other specified hypofunction or disorders of pituitary gland

Foundation entity

Hypopituitarism – http://id.who.int/icd/entity/768216194

Part of: 5A61: Hypofunction or certain other specified disorders of pituitary gland › 05: Endocrine, nutritional or metabolic diseases