6C42.2ICD-11 MMS 2026-01
Synthetic cannabinoid dependence
Description
Synthetic cannabinoid dependence is a disorder of regulation of synthetic cannabinoid use arising from repeated or continuous use of synthetic cannabinoids. The characteristic feature is a strong internal drive to use synthetic cannabinoids, which is manifested by impaired ability to control use, increasing priority given to use over other activities and persistence of use despite harm or negative consequences. These experiences are often accompanied by a subjective sensation of urge or craving to use synthetic cannabinoids. Physiological features of dependence may also be present, including tolerance to the effects of synthetic cannabinoids, withdrawal symptoms following cessation or reduction in use of synthetic cannabinoids, or repeated use of synthetic cannabinoids or pharmacologically similar substances to prevent or alleviate withdrawal symptoms. The features of dependence are usually evident over a period of at least 12 months but the diagnosis may be made if synthetic cannabinoid use is continuous (daily or almost daily) for at least 3 months.
Excludes
Exclusions from above levels
Child codes
6C42.20– Synthetic cannabinoid dependence, current use6C42.21– Synthetic cannabinoid dependence, early full remission6C42.22– Synthetic cannabinoid dependence, sustained partial remission6C42.23– Synthetic cannabinoid dependence, sustained full remission6C42.2Y– Other specified synthetic cannabinoid dependence6C42.2Z– Synthetic cannabinoid dependence, unspecified
Sibling codes
6C42.0– Episode of harmful use of synthetic cannabinoids6C42.1– Harmful pattern of use of synthetic cannabinoids6C42.3– Synthetic cannabinoid intoxication6C42.4– Synthetic cannabinoid withdrawal6C42.5– Synthetic cannabinoid-induced delirium6C42.6– Synthetic cannabinoid-induced psychotic disorder6C42.7– Certain specified synthetic cannabinoids-induced mental or behavioural disorders6C42.Y– Other specified disorders due to use of synthetic cannabinoids6C42.Z– Disorders due to use of synthetic cannabinoids, unspecified
Foundation entity
Synthetic cannabinoid dependence – http://id.who.int/icd/entity/686500513
Allowed postcoordination axes
Part of: 6C42: Disorders due to use of synthetic cannabinoids › 06: Mental, behavioural or neurodevelopmental disorders