6C42.4

ICD-11 MMS 2026-01

Synthetic cannabinoid withdrawal

Description

Synthetic cannabinoid withdrawal is a clinically significant cluster of symptoms, behaviours and/or physiological features, varying in degree of severity and duration, that occurs upon cessation or reduction of use of synthetic cannabinoids in individuals who have developed Synthetic cannabinoid dependence or have used synthetic cannabinoids for a prolonged period or in large amounts. Presenting features of Synthetic cannabinoid withdrawal may include irritability, anger, aggression, shakiness, insomnia and disturbing dreams, restlessness, anxiety, depressed mood and appetite disturbance. In the early phase, Synthetic cannabinoid withdrawal may be accompanied by residual features of intoxication from the drug, such as paranoid ideation and auditory and visual hallucinations.

Index terms

  • Synthetic cannabinoid withdrawal

Exclusions from above levels

  • 6C41 – Disorders due to use of cannabis
  • QE62 – Uncomplicated bereavement
  • QE84 – Acute stress reaction

Sibling codes

  • 6C42.0 – Episode of harmful use of synthetic cannabinoids
  • 6C42.1 – Harmful pattern of use of synthetic cannabinoids
  • 6C42.2 – Synthetic cannabinoid dependence
  • 6C42.3 – Synthetic cannabinoid intoxication
  • 6C42.5 – Synthetic cannabinoid-induced delirium
  • 6C42.6 – Synthetic cannabinoid-induced psychotic disorder
  • 6C42.7 – Certain specified synthetic cannabinoids-induced mental or behavioural disorders
  • 6C42.Y – Other specified disorders due to use of synthetic cannabinoids
  • 6C42.Z – Disorders due to use of synthetic cannabinoids, unspecified

Foundation entity

Synthetic cannabinoid withdrawal – http://id.who.int/icd/entity/397276103

Allowed postcoordination axes

Part of: 6C42: Disorders due to use of synthetic cannabinoids › 06: Mental, behavioural or neurodevelopmental disorders