6C45.2ICD-11 MMS 2026-01
Cocaine dependence
Description
Cocaine dependence is a disorder of regulation of cocaine use arising from repeated or continuous use of cocaine. The characteristic feature is a strong internal drive to use cocaine, which is manifested by impaired ability to control use, increasing priority given to use over other activities and persistence of use despite harm or negative consequences. These experiences are often accompanied by a subjective sensation of urge or craving to use cocaine. Physiological features of dependence may also be present, including tolerance to the effects of cocaine, withdrawal symptoms following cessation or reduction in use of cocaine, or repeated use of cocaine or pharmacologically similar substances to prevent or alleviate withdrawal symptoms. The features of dependence are usually evident over a period of at least 12 months but the diagnosis may be made if cocaine use is continuous (daily or almost daily) for at least 3 months.
Excludes
Exclusions from above levels
6C46– Disorders due to use of stimulants including amphetamines, methamphetamine or methcathinoneQE11.3– Hazardous use of cocaineQE62– Uncomplicated bereavement
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QE84– Acute stress reaction
Child codes
Sibling codes
6C45.0– Episode of harmful use of cocaine6C45.1– Harmful pattern of use of cocaine6C45.3– Cocaine intoxication6C45.4– Cocaine withdrawal6C45.5– Cocaine-induced delirium6C45.6– Cocaine-induced psychotic disorder6C45.7– Certain specified cocaine-induced mental or behavioural disorders6C45.Y– Other specified disorders due to use of cocaine6C45.Z– Disorders due to use of cocaine, unspecified
Foundation entity
Cocaine dependence – http://id.who.int/icd/entity/1691013484
Allowed postcoordination axes
Part of: 6C45: Disorders due to use of cocaine › 06: Mental, behavioural or neurodevelopmental disorders