6C45.3

ICD-11 MMS 2026-01

Cocaine intoxication

Description

Cocaine intoxication is a clinically significant transient condition that develops during or shortly after the consumption of cocaine that is characterised by disturbances in consciousness, cognition, perception, affect, behaviour, or coordination. These disturbances are caused by the known pharmacological effects of cocaine and their intensity is closely related to the amount of cocaine consumed. They are time-limited and abate as cocaine is cleared from the body. Presenting features may include inappropriate euphoria, anxiety, anger, impaired attention, hypervigilance, psychomotor agitation, paranoid ideation (sometimes of delusional intensity), auditory hallucinations, confusion, and changes in sociability. Perspiration or chills, nausea or vomiting, and palpitations and chest pain may be experienced. Physical signs may include tachycardia, elevated blood pressure, and pupillary dilatation. In rare instances, usually in severe intoxication, cocaine use can result in seizures, muscle weakness, dyskinesia, or dystonia.

Index terms

  • Cocaine intoxication
  • acute cocaine intoxication
  • bad trip due to cocaine

Excludes

  • 6B63 – Possession trance disorder
  • NE60 – cocaine poisoning

Exclusions from above levels

  • 6C46 – Disorders due to use of stimulants including amphetamines, methamphetamine or methcathinone
  • QE11.3 – Hazardous use of cocaine
  • QE62 – Uncomplicated bereavement
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  • QE84 – Acute stress reaction

Sibling codes

  • 6C45.0 – Episode of harmful use of cocaine
  • 6C45.1 – Harmful pattern of use of cocaine
  • 6C45.2 – Cocaine dependence
  • 6C45.4 – Cocaine withdrawal
  • 6C45.5 – Cocaine-induced delirium
  • 6C45.6 – Cocaine-induced psychotic disorder
  • 6C45.7 – Certain specified cocaine-induced mental or behavioural disorders
  • 6C45.Y – Other specified disorders due to use of cocaine
  • 6C45.Z – Disorders due to use of cocaine, unspecified

Foundation entity

Cocaine intoxication – http://id.who.int/icd/entity/1965837313

Allowed postcoordination axes

Part of: 6C45: Disorders due to use of cocaine › 06: Mental, behavioural or neurodevelopmental disorders