6C4G.2

ICD-11 MMS 2026-01

Unknown or unspecified psychoactive substance dependence

Description

Unknown or unspecified psychoactive substance dependence is a disorder of regulation of use of an unknown or unspecified substance arising from repeated or continuous use of the substance. The characteristic feature is a strong internal drive to use the unknown or unspecified substance, which is manifested by impaired ability to control use, increasing priority given to use over other activities and persistence of use despite harm or negative consequences. These experiences are often accompanied by a subjective sensation of urge or craving to use the unknown or unspecified substance. The features of dependence are usually evident over a period of at least 12 months but the diagnosis may be made if use of the unknown or unspecified substance is continuous (daily or almost daily) for at least 3 months.

Excludes

  • 6C4G.0 – Episode of harmful use of unknown or unspecified psychoactive substances
  • 6C4G.1 – Harmful pattern of use of unknown or unspecified psychoactive substance

Exclusions from above levels

  • QE62 – Uncomplicated bereavement
  • QE84 – Acute stress reaction

Child codes

  • 6C4G.20 – Unknown or unspecified psychoactive substance dependence, current use
  • 6C4G.21 – Unknown or unspecified psychoactive substance dependence, early full remission
  • 6C4G.22 – Unknown or unspecified psychoactive substance dependence, sustained partial remission
  • 6C4G.23 – Unknown or unspecified psychoactive substance dependence, sustained full remission
  • 6C4G.2Z – Unknown or unspecified psychoactive substance dependence, substance and state of remission unspecified

Sibling codes

  • 6C4G.0 – Episode of harmful use of unknown or unspecified psychoactive substances
  • 6C4G.1 – Harmful pattern of use of unknown or unspecified psychoactive substance
  • 6C4G.3 – Intoxication due to unknown or unspecified psychoactive substance
  • 6C4G.4 – Withdrawal due to unknown or unspecified psychoactive substance
  • 6C4G.5 – Delirium induced by unknown or unspecified psychoactive substance
  • 6C4G.6 – Psychotic disorder induced by unknown or unspecified psychoactive substance
  • 6C4G.7 – Certain unknown or unspecified psychoactive substance-induced mental or behavioural disorders
  • 6C4G.Y – Other specified disorders due to use of unknown or unspecified psychoactive substances
  • 6C4G.Z – Disorders due to use of unknown or unspecified psychoactive substances, unspecified

Foundation entity

Unknown or unspecified psychoactive substance dependence – http://id.who.int/icd/entity/2143971168

Allowed postcoordination axes

Part of: 6C4G: Disorders due to use of unknown or unspecified psychoactive substances › 06: Mental, behavioural or neurodevelopmental disorders