6C4G.4

ICD-11 MMS 2026-01

Withdrawal due to unknown or unspecified psychoactive substance

Description

Withdrawal due to unknown or unspecified psychoactive substance is a clinically significant cluster of symptoms, behaviours and/or physiological features, varying in degree of severity and duration, that occurs upon cessation or reduction of use of an unknown or unspecified substance in individuals who have developed dependence or have used the unknown or unspecified substance for a prolonged period or in large amounts. Withdrawal due to unknown or unspecified psychoactive substance can also occur when prescribed psychoactive medications have been used in standard therapeutic doses. The specific features of the withdrawal state depend on the pharmacological properties of the unknown or unspecified substance.

Exclusions from above levels

  • QE62 – Uncomplicated bereavement
  • QE84 – Acute stress reaction

Child codes

  • 6C4G.40 – Withdrawal due to unknown or unspecified psychoactive substance, uncomplicated
  • 6C4G.41 – Withdrawal due to unknown or unspecified psychoactive substance, with perceptual disturbances
  • 6C4G.42 – Withdrawal due to unknown or unspecified psychoactive substance, with seizures
  • 6C4G.43 – Withdrawal due to unknown or unspecified psychoactive, with perceptual disturbances and seizures
  • 6C4G.4Z – Withdrawal due to unknown or unspecified psychoactive substance, unspecified

Sibling codes

  • 6C4G.0 – Episode of harmful use of unknown or unspecified psychoactive substances
  • 6C4G.1 – Harmful pattern of use of unknown or unspecified psychoactive substance
  • 6C4G.2 – Unknown or unspecified psychoactive substance dependence
  • 6C4G.3 – Intoxication due to unknown or unspecified psychoactive substance
  • 6C4G.5 – Delirium induced by unknown or unspecified psychoactive substance
  • 6C4G.6 – Psychotic disorder induced by unknown or unspecified psychoactive substance
  • 6C4G.7 – Certain unknown or unspecified psychoactive substance-induced mental or behavioural disorders
  • 6C4G.Y – Other specified disorders due to use of unknown or unspecified psychoactive substances
  • 6C4G.Z – Disorders due to use of unknown or unspecified psychoactive substances, unspecified

Foundation entity

Withdrawal due to unknown or unspecified psychoactive substance – http://id.who.int/icd/entity/219731531

Allowed postcoordination axes

Part of: 6C4G: Disorders due to use of unknown or unspecified psychoactive substances › 06: Mental, behavioural or neurodevelopmental disorders