8C72.01

ICD-11 MMS 2026-01

Centronuclear myopathy

Description

Centronuclear myopathy (CNM) is an inherited neuromuscular disorder characterised by clinical features of a congenital myopathy and centrally placed nuclei on muscle biopsy. It encompasses the X-linked form, the autosomal recessive form and the autosomal dominant form with a highly variable clinical presentation.

Index terms

  • Centronuclear myopathy
  • Autosomal recessive centronuclear myopathy
  • Centronuclear myopathy with type I fibre hypotrophy
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  • Autosomal dominant centronuclear myopathy
  • Severe infantile myotubular myopathy
  • Myotubular myopathy
  • myotubular centronuclear myopathy
  • severe x-linked myotubular myopathy
  • x-linked centronuclear myopathy

Exclusions from above levels

  • http://id.who.int/icd/entity/1159616108 – Secondary myopathies
  • http://id.who.int/icd/entity/1425591047 – Myasthenia gravis or certain specified neuromuscular junction disorders
  • http://id.who.int/icd/entity/155258022 – Metabolic disorders
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  • LD26.41 – Arthrogryposis multiplex congenita
  • 05 – Endocrine, nutritional or metabolic diseases
  • 18 – Complications of pregnancy, childbirth and the puerperium
  • 19 – Certain conditions originating in the perinatal period
  • 22 – Injury, poisoning or certain other consequences of external causes

Sibling codes

  • 8C72.00 – Nemaline myopathy
  • 8C72.02 – Central core disease
  • 8C72.0Y – Other specified congenital myopathy with structural abnormalities
  • 8C72.0Z – Congenital myopathy with structural abnormalities, unspecified

Foundation entity

Centronuclear myopathy – http://id.who.int/icd/entity/742097637

Part of: 8C72.0: Congenital myopathy with structural abnormalities › 8C72: Congenital myopathies › 08: Diseases of the nervous system