8D84

ICD-11 MMS 2026-01

Pure autonomic nervous system failure

Description

Pure autonomic failure is a sporadic, adult onset, slowly progressive disorder associated with accumulation of synuclein in peripheral autonomic neurons resulting in orthostatic hypotension, bladder and sexual dysfunction.

Index terms

  • Pure autonomic nervous system failure
  • Bradbury-Eggleston syndrome
  • Idiopathic orthostatic hypotension

Exclusions from above levels

  • 05 – Endocrine, nutritional or metabolic diseases
  • 18 – Complications of pregnancy, childbirth and the puerperium
  • 19 – Certain conditions originating in the perinatal period
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  • 22 – Injury, poisoning or certain other consequences of external causes

Sibling codes

  • 8D80 – Congenital malformations of the autonomic nervous system
  • 8D81 – Inherited autonomic nervous system disorders
  • 8D82 – Autoimmune disorders involving the autonomic nervous system
  • 8D83 – Autonomic nervous system disorder due to infection
  • 8D85 – Autonomic nervous system disorder due to substances
  • 8D86 – Autonomic nervous system hyperactivity
  • 8D87 – Autonomic nervous system disorder due to certain specified neurodegenerative disorder
  • 8D88 – Autonomic neuropathies
  • 8D89 – Disorders of orthostatic tolerance
  • 8D8A – Focal or segmental autonomic disorders
  • 8D8B – Disorders affecting autonomic synaptic neurotransmission
  • 8D8C – Autonomic dysreflexia
  • 8D8D – Hypoglycaemia unawareness
  • 8D8Y – Other specified disorders of autonomic nervous system
  • 8D8Z – Disorders of autonomic nervous system, unspecified

Foundation entity

Pure autonomic nervous system failure – http://id.who.int/icd/entity/734022291

Part of: 08: Diseases of the nervous system