CA08

ICD-11 MMS 2026-01

Vasomotor or allergic rhinitis

Description

Rhinitis is inflammation of the nasal mucosa clinically characterised by major symptoms: sneezing, nasal pruritus, running nose, and stuffy nose. Allergic rhinitis is an inflammation of nasal airway triggered by allergens to which the affected individual has previously been sensitized. Pathogenesis of allergic rhinitis is type I allergy on the nasal mucosa. Antigens inhaled into sensitized nasal mucosa bind to IgE antibodies on mast cells, which release chemical mediators such as histamine and peptide leukotriene. Consequently terminal of sensory neurons and vessels react to induce sneezing, running nose, and stuffy nose (immediate phase reaction). In late phase reaction, various chemical mediators are produced by mast cells, cytokines are produced by Th2 and mast cells, and chemokines are produced by epithelial cells, endothelium of blood vessels, and fibrocytes, respectively. These cell-derived transmitters actually induce various cell types of inflammatory cell infiltration to nasal mucosa. Among them, activated eosinophils is the main player of mucosal swelling and hyperreactivity. Non-allergic rhinitis is an inflammation of nasal mucosa in which allergic mechanisms are not involved. It covers many different phenotypes.

Index terms

  • Vasomotor or allergic rhinitis

Excludes

Exclusions from above levels

  • CA22.0 – Chronic obstructive pulmonary disease with acute exacerbation, unspecified
  • 01 – Certain infectious or parasitic diseases
  • 05 – Endocrine, nutritional or metabolic diseases
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  • 18 – Complications of pregnancy, childbirth and the puerperium
  • 19 – Certain conditions originating in the perinatal period
  • 20 – Congenital malformations, deformations and chromosomal abnormalities
  • 22 – Injury, poisoning or certain other consequences of external causes

Child codes

Sibling codes

  • CA00 – Acute nasopharyngitis
  • CA01 – Acute sinusitis
  • CA02 – Acute pharyngitis
  • CA03 – Acute tonsillitis
  • CA04 – Acute laryngopharyngitis
  • CA05 – Acute laryngitis or tracheitis
  • CA06 – Acute obstructive laryngitis or epiglottitis
  • CA07 – Acute upper respiratory infections of multiple and unspecified sites
  • CA09 – Chronic rhinitis, nasopharyngitis or pharyngitis
  • CA0A – Chronic rhinosinusitis
  • CA0B – Silent sinus syndrome
  • CA0C – Cyst or mucocele of nose or nasal sinus
  • CA0D – Deviated nasal septum
  • CA0E – Hypertrophy of nasal turbinates
  • CA0F – Chronic diseases of tonsils or adenoids
  • CA0G – Chronic laryngitis or laryngotracheitis
  • CA0H – Diseases of vocal cords or larynx, not elsewhere classified
  • CA0J – Nasal polyp
  • CA0K – Abscess of upper respiratory tract
  • CA0Y – Other specified upper respiratory tract disorders
  • CA0Z – Upper respiratory tract disorders, unspecified

Foundation entity

Vasomotor or allergic rhinitis – http://id.who.int/icd/entity/2090379743

Part of: 12: Diseases of the respiratory system