DA03.5

ICD-11 MMS 2026-01

Macroglossia

Description

Macroglossia is the medical term for a large or enlarged tongue. It may be due to a variety of congenital and acquired conditions. Isolated macroglossia has no determinable cause. It is seen commonly in Down syndrome. The most common causes of tongue enlargement are vascular malformations (e.g. lymphangioma or haemangioma) and muscular hypertrophy. It may, however, be due to infiltration, as with primary systemic amyloidosis.

Index terms

  • Macroglossia
  • acquired macroglossia NOS

Exclusions from above levels

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  • DA02.2 – submucous fibrosis of tongue
  • LA31.2 – Ankyloglossia
  • 01 – Certain infectious or parasitic diseases
  • 02 – Neoplasms
  • 05 – Endocrine, nutritional or metabolic diseases
  • 06 – Mental, behavioural or neurodevelopmental disorders
  • 18 – Complications of pregnancy, childbirth and the puerperium
  • 22 – Injury, poisoning or certain other consequences of external causes

Foundation children elsewhere

  • LA31.0 – Congenital macroglossia

Sibling codes

  • DA03.0 – Glossitis
  • DA03.1 – Geographic tongue
  • DA03.2 – Atrophy of tongue papillae
  • DA03.3 – Median rhomboid glossitis
  • DA03.4 – Hypertrophy of tongue papillae
  • DA03.Y – Other specified diseases of tongue
  • DA03.Z – Diseases of tongue, unspecified

Foundation entity

Macroglossia – http://id.who.int/icd/entity/670519908

Part of: DA03: Diseases of tongue › 13: Diseases of the digestive system