DA94.22

ICD-11 MMS 2026-01

Food protein-induced enterocolitis syndrome

Description

A non-IgE-mediated intestinal hypersensitivity cell-mediated persistent chronic inflammation of the enteric tract which primarily affects children. The most common causal foods are: cow’s milk, soy, rice, oat, meat. In cases of chronic exposure, the most frequent symptoms are emesis, diarrhoea, poor growth and lethargy. In cases of re-exposure after restriction, the patient can present emesis, diarrhoea, hypotension (15%) 2 hours after ingestion.

Index terms

  • Food protein-induced enterocolitis syndrome
  • FPIES - [Food protein-induced enterocolitis syndrome]

Exclusions from above levels

  • DD70.1 – Crohn disease of small intestine
  • DD91.2 – Functional diarrhoea
  • KB8C – Noninfectious neonatal diarrhoea
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  • DE12.0 – Ileostomy malfunction
  • http://id.who.int/icd/entity/1195691020 – Diseases of duodenum
  • 01 – Certain infectious or parasitic diseases
  • 02 – Neoplasms
  • 05 – Endocrine, nutritional or metabolic diseases
  • 06 – Mental, behavioural or neurodevelopmental disorders
  • 18 – Complications of pregnancy, childbirth and the puerperium
  • 22 – Injury, poisoning or certain other consequences of external causes

Sibling codes

  • DA94.20 – IgE mediated allergic enteritis of small intestine
  • DA94.21 – Eosinophilic enteritis
  • DA94.2Y – Other specified allergic or dietetic enteritis of small intestine
  • DA94.2Z – Allergic or dietetic enteritis of small intestine, unspecified

Foundation entity

Food protein-induced enterocolitis syndrome – http://id.who.int/icd/entity/1729235847

Allowed postcoordination axes

Part of: DA94.2: Allergic or dietetic enteritis of small intestine › DA94: Noninfectious enteritis or ulcer of small intestine › 13: Diseases of the digestive system