DB95.0

ICD-11 MMS 2026-01

Drug-induced or toxic liver disease with acute hepatic necrosis or acute hepatitis

Description

This is an acute hepatocellular injury that develops within 1 to 20 weeks after starting treatment. The histological lesions consist mainly of focal, zonal or bridging necrosis, but lobular and portal tract inflammation evident with drug hepatitis. Extrahepatic features of drug hypersensitivity, including rash, lymphadenopathy, eosinophilia or other systemic features, are observed in some cases.

Index terms

  • Drug-induced or toxic liver disease with acute hepatic necrosis or acute hepatitis
  • Drug-induced or toxic liver disease with acute hepatic necrosis or acute hepatitis, with complications
  • Drug-induced or toxic liver disease with acute hepatic necrosis or acute hepatitis, without complications

Exclusions from above levels

  • DB94 – Alcoholic liver disease
  • DB98.5 – Budd-Chiari syndrome
  • ME10.1 – Unspecified jaundice
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  • 01 – Certain infectious or parasitic diseases
  • 02 – Neoplasms
  • 05 – Endocrine, nutritional or metabolic diseases
  • 06 – Mental, behavioural or neurodevelopmental disorders
  • 18 – Complications of pregnancy, childbirth and the puerperium
  • 22 – Injury, poisoning or certain other consequences of external causes

Sibling codes

  • DB95.1 – Drug-induced or toxic liver disease with chronic hepatitis
  • DB95.2 – Drug-induced or toxic liver disease with cholestasis
  • DB95.3 – Drug-induced or toxic liver disease with fatty liver
  • DB95.4 – Drug-induced or toxic liver disease with granulomatous hepatitis
  • DB95.5 – Drug-induced or toxic liver disease with fibrosis or cirrhosis of liver
  • DB95.6 – Drug-induced or toxic liver disease with vascular disorders of the liver
  • DB95.7 – Drug-induced or toxic liver disease with liver tumours
  • DB95.Y – Other specified drug-induced or toxic liver disease
  • DB95.Z – Drug-induced or toxic liver disease, unspecified

Foundation entity

Drug-induced or toxic liver disease with acute hepatic necrosis or acute hepatitis – http://id.who.int/icd/entity/1711029358

Allowed postcoordination axes

Part of: DB95: Drug-induced or toxic liver disease › 13: Diseases of the digestive system