EA50.2

ICD-11 MMS 2026-01

Staphylococcal scalded skin syndrome

Description

A syndrome caused by an infection with the gram-positive bacteria Staphylococcus. This syndrome is characterised by fever, blisters, erythema, large areas of skin peel, or Nikolsky’s sign. Transmission is by direct or indirect contact with an infected individual, through fomites, or by iatrogenic transmission. Confirmation is by identification of Staphylococcus in a blood or skin sample.

Index terms

  • Staphylococcal scalded skin syndrome
  • Ritter disease
  • SSSS - [staphylococcal scalded skin syndrome]
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  • Pemphigus neonatorum

Excludes

  • EB13.1 – Toxic epidermal necrolysis

Exclusions from above levels

  • QD04 – Asymptomatic colonization of the skin by virulent or therapy resistant bacteria

Sibling codes

  • EA50.0 – Erythema marginatum rheumaticum
  • EA50.1 – Streptococcal toxin-mediated perineal erythema
  • EA50.3 – Staphylococcal scarlatina
  • EA50.Y – Other specified toxin-mediated cutaneous reactions to distant or systemic bacterial infection
  • EA50.Z – Toxin-mediated cutaneous reactions to distant or systemic bacterial infection, unspecified

Foundation entity

Staphylococcal scalded skin syndrome – http://id.who.int/icd/entity/1554593739

Part of: EA50: Toxin-mediated cutaneous reactions to distant or systemic bacterial infection › 14: Diseases of the skin