ED51.00

ICD-11 MMS 2026-01

Benign acanthosis nigricans

Description

Benign acanthosis nigricans is a thickening and pigmentation affecting predominantly flexural skin, especially the neck, axillae and groins. It is thought to be due to high concentrations of insulin binding to insulin-like growth factor receptors, with resultant keratinocyte proliferation. It is strongly associated with insulin resistance and obesity. Type 2 diabetes and the metabolic syndrome are commonly associated.

Index terms

  • Benign acanthosis nigricans
  • Acanthosis nigricans associated with Type II diabetes and obesity

Excludes

  • EL10 – Paraneoplastic acanthosis nigricans

Sibling codes

  • ED51.0Y – Other specified acanthosis nigricans
  • ED51.0Z – Acanthosis nigricans, unspecified

Foundation entity

Benign acanthosis nigricans – http://id.who.int/icd/entity/1181289910

Part of: ED51.0: Acanthosis nigricans › ED51: Diffuse epidermal hyperkeratosis or acanthosis › 14: Diseases of the skin