Catalog
Benign acanthosis nigricans
Link to WHO Definition
Benign acanthosis nigricans – http://id.who.int/icd/entity/1181289910
Benign acanthosis nigricans is a thickening and pigmentation affecting predominantly flexural skin, especially the neck, axillae and groins. It is thought to be due to high concentrations of insulin binding to insulin-like growth factor receptors, with resultant keratinocyte proliferation. It is strongly associated with insulin resistance and obesity. Type 2 diabetes and the metabolic syndrome are commonly associated.