KB61.3

ICD-11 MMS 2026-01

Neonatal osteopenia

Description

Metabolic bone disease is a common complication in very low birthweight (VLBW) preterm infants. The smallest, sickest infants are at greatest risk. Progressive osteopenia with demineralized bones and, occasionally, pathologic fractures may develop. The major cause is inadequate intake of calcium and phosphorus to meet the requirements for growth. Poor intake of vitamin D is an additional risk factor. Contributing factors include prolonged parenteral nutrition, vitamin D and calcium malabsorption, intake of unsupplemented human milk, immobilization, and urinary calcium losses from long-term diuretic use.

Coding note from above levels

Conditions arising in the perinatal period, even though death or morbidity occurs later, should, as far as possible, be coded to chapter 19, which takes precedence over chapters containing codes for diseases by their anatomical site. For children less than 28 days old, assume that a reported condition developed in the perinatal period, unless the duration is stated and the onset was after the first completed week of life.

Index terms

  • Neonatal osteopenia

Exclusions from above levels

  • 01 – Certain infectious or parasitic diseases - acquired after birth
  • 02 – Neoplasms
  • 05 – Endocrine, nutritional or metabolic diseases
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  • 08 – Certain congenital diseases of the nervous system
  • 20 – Congenital malformations, deformations and chromosomal abnormalities
  • 22 – Injury, poisoning or certain other consequences of external causes
  • 3A10 – Hereditary haemolytic anaemia
  • 4A01.03 – Transient hypogammaglobulinaemia of infancy
  • 9B71.3 – Retinopathy of prematurity
  • BC43 – congenital cardiomyopathy
  • DA93.0 – Paralytic ileus
  • EA50.Z – Pemphigus neonatorum
  • EH40.00 – Cradle cap
  • http://id.who.int/icd/entity/588616678 – Gastroenteritis or colitis of infectious origin
  • http://id.who.int/icd/entity/609214049 – Congenital gonococcal infection

Sibling codes

  • KB61.0 – Neonatal hypomagnesaemia
  • KB61.1 – Neonatal tetany without calcium or magnesium deficiency
  • KB61.2 – Neonatal hypocalcaemia
  • KB61.Y – Other specified transitory neonatal disorders of calcium or magnesium metabolism
  • KB61.Z – Transitory neonatal disorders of calcium or magnesium metabolism, unspecified

Foundation entity

Neonatal osteopenia – http://id.who.int/icd/entity/109776301

Part of: KB61: Transitory neonatal disorders of calcium or magnesium metabolism › 19: Certain conditions originating in the perinatal period