Catalog

Neonatal myasthenia gravis

No MMS code

Link to WHO Definition

Neonatal myasthenia gravis – http://id.who.int/icd/entity/1274860004

Neonatal Myasthenia Gravis (MG) refers to the clinical MG syndrome caused by passively transferred maternal auto-antibodies to the newborn. This disease mechanism has been described for all three major forms of MG, including Acetylcholine receptor, Muscle-specific kinase and Lambert-Eaton myasthenic syndrome antibodies. Frequency is 10-30%. The neonates present with weakness, hypotonia, respiratory depression. The symptoms subside over 1 to 4 weeks.