Catalog
Myasthenia gravis
Link to WHO Definition
Myasthenia gravis – http://id.who.int/icd/entity/1270100227
Myasthenia gravis is the most common acquired auto-antibody mediated neuromuscular transmission disorder. Prevalence is 1–2 per 10,000 persons. Fluctuating weakness increasing with repeated activity and improving after a period of rest is the hallmark. Myasthenia Gravis with antibodies directed against postsynaptic proteins, usually the nicotinic acetylcholine receptor are the most prevalent. Other types are Myasthenia Gravis associated with muscle-specific kinase antibodies and MG with unknown autoantibodies (seronegative) Myasthenia Gravis. There are three groups: 1. Purely ocular Myasthenia Gravis 2. Early-onset (<40-50 years) generalised Myasthenia Gravis 3. Late-onset generalised MG. In about 15%, the disease can be classified as paraneoplastic, usually associated with a thymoma.
Parents
Children
- Myasthenia gravis, autoimmune acquired
- Neonatal myasthenia gravis
- Myasthenia gravis, familial
- Myasthenia gravis, seronegative
- Myasthenia gravis, other antibodies positive
- KB08.0 Transient neonatal myasthenia gravis
- Rippling muscle disease with myasthenia gravis
- Myasthenia gravis, AChR antibody positive
- Myasthenia gravis, MuSK antibody positive
- 8C60.0 Drug-induced myasthenia gravis
- Thymoma-associated myasthenia gravis