Catalog

Primary cutaneous CD4-positive small or intermediate pleomorphic T-cell lymphoproliferative disorder

No MMS code

Link to WHO Definition

Primary cutaneous CD4-positive small or intermediate pleomorphic T-cell lymphoproliferative disorder – http://id.who.int/icd/entity/1278180128

This reactive lymphoproliferative disorder usually presents with a solitary plaque or tumour on the face, neck, or upper trunk. Morphologically, it is composed of small to medium-sized CD4-positive, CD8-negative, and CD30-negative pleomorphic T-lymphocytes. A small number of large pleomorphic T-lymphocytes may also be present. The lymphocytic infiltrate is dermal. Focal epidermotropism and subcutaneous involvement may be present. It has a favourable prognosis.