Catalog

Juvenile polymyositis, necrotising

No MMS code

Link to WHO Definition

Juvenile polymyositis, necrotising – http://id.who.int/icd/entity/1627905326

Juvenile necrotizing polymyositis is an early-onset immune inflammatory muscle disorders characterised by high CK level, moderate to severe muscle weakness of acute or subacute onset and with histological features of muscle fibre necrosis mediated by macrophages as the main effector cell. There are no T cell infiltrates or MHC-I expression. However, some patients have antibodies against signal recognition particles (SRP).