Catalog

Juvenile polymyositis with anti-synthetase auto-antibody

No MMS code

Link to WHO Definition

Juvenile polymyositis with anti-synthetase auto-antibody – http://id.who.int/icd/entity/1799798848

Juvenile polymyositis with anti-synthetase auto-antibody is a rare childhood idiopathic inflammatory myopathy associated with anti-synthetase autoantibody, being the anti-Jo-1 the most common autoantibody. These patients have a constellation of symptoms, including myalgias, muscle weakness, and a combination of "core" symptoms, including interstitial lung disease, Raynaud phenomenon, seronegative arthritis of the distal joints, fever, mechanic’s hands, and a skin rash different from the heliotrope erythema seen in dermatomyositis.