Catalog
Neuromyelitis optica aquaporin-4 antibody negative
Link to WHO Definition
Neuromyelitis optica aquaporin-4 antibody negative – http://id.who.int/icd/entity/869136080
Neuromyelitis optica (NMO) is an inflammatory demyelinating disease of the central nervous system characterised mainly by attacks of uni- or bilateral optic neuritis (ON) and acute longitudinally extensive (> 3 vertebral segments) myelitis. This form is seronegative for aquaporin-4 antibodies. Some patients may be myelin oligodendrocyte glycoprotein (MOG) antibody positive.