Neuromyelitis optica aquaporin-4 antibody negative

Description

Neuromyelitis optica (NMO) is an inflammatory demyelinating disease of the central nervous system characterised mainly by attacks of uni- or bilateral optic neuritis (ON) and acute longitudinally extensive (> 3 vertebral segments) myelitis. This form is seronegative for aquaporin-4 antibodies. Some patients may be myelin oligodendrocyte glycoprotein (MOG) antibody positive.

Index terms

Neuromyelitis optica aquaporin-4 antibody negative
AQP-4 negative optical neuromyelitis

Exclusions from above levels

05 – Endocrine, nutritional or metabolic diseases
18 – Complications of pregnancy, childbirth and the puerperium
19 – Certain conditions originating in the perinatal period

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22 – Injury, poisoning or certain other consequences of external causes

Sibling codes

8A43.0 – Neuromyelitis optica aquaporin-4 antibody positive
8A43.2 – Single transverse myelitis aquaporin-4 antibody positive
8A43.3 – Recurrent transverse myelitis aquaporin-4 antibody positive
8A43.4 – Single optic neuritis aquaporin-4 antibody positive
8A43.5 – Recurrent optic neuritis aquaporin-4 antibody positive
8A43.Y – Other specified neuromyelitis optica
8A43.Z – Neuromyelitis optica, unspecified

Foundation entity

Neuromyelitis optica aquaporin-4 antibody negative – http://id.who.int/icd/entity/869136080

Part of: 8A43: Neuromyelitis optica › 08: Diseases of the nervous system