1E50.3

ICD-11 MMS 2026-01

Acute hepatitis D

Description

Acute liver injury and inflammation caused by recent and short-term (less than 6 months) infection with hepatitis D virus (HDV). Transmission only occurs in someone with chronic HBV infection (super-infection) or at the same time as acute hepatitis B (co-infection), and is by blood and body fluid contamination (parenteral spread), and sexual spread. Diagnosis is confirmed by serum IgM-anti-HDV. Clinical features, if they occur, are characterised by anorexia, nausea and fever, with jaundice in severe cases. Acute liver failure occurs in some cases, and a high proportion of cases develops chronic HDV infection.

Index terms

  • Acute hepatitis D
  • Acute hepatitis D, through super-infection of hepatitis B carrier

Exclusions from above levels

  • 1E51 – Chronic viral hepatitis
  • DB90 – Infectious liver disease
  • DB91 – Acute or subacute hepatic failure
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  • 1F00.Y – Herpes simplex hepatitis
  • DB92.1 – Non-alcoholic steatohepatitis
  • DB96.0 – Autoimmune hepatitis
  • NE83.1 – Infection arising from device, implant or graft, not elsewhere classified

Sibling codes

  • 1E50.0 – Acute hepatitis A
  • 1E50.1 – Acute hepatitis B
  • 1E50.2 – Acute hepatitis C
  • 1E50.4 – Acute hepatitis E
  • 1E50.Y – Other specified acute viral hepatitis
  • 1E50.Z – Acute viral hepatitis, unspecified

Foundation entity

Acute hepatitis D – http://id.who.int/icd/entity/1060335896

Part of: 1E50: Acute viral hepatitis › 01: Certain infectious or parasitic diseases