DB92.1ICD-11 MMS 2026-01
Non-alcoholic steatohepatitis
Description
Non-alcoholic steatohepatitis (NASH) is a histological form of Non-alcoholic fatty liver disease (NAFLD) in which the key features are histological evidence of hepatocyte injury (such as ballooning or Mallory hyaline) and substantial lobular inflammation. NASH is often associated with fibrosis in pericentral and perisinusoidal distribution (a portal fibrosis pattern also exists, particularly in children). NASH is the clinically progressive form of NAFLD with clinical outcomes including cardiovascular events, and cirrhosis or hepatocellular carcinoma. While novel biomarkers for NASH have been reported, histology remains the gold standard for diagnosis.
Index terms
- Non-alcoholic steatohepatitis
- NASH - [non-alcoholic steatohepatitis]
- non-alcoholic steatohepatosis
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- Non-alcoholic steatohepatitis with cirrhosis
- NASH with cirrhosis
- Non-alcoholic steatohepatitis with fibrosis
- NASH without cirrhosis
- Non-alcoholic steatohepatitis without cirrhosis or fibrosis
- NASH without mention of cirrhosis
Exclusions from above levels
1E51.1– Chronic hepatitis C5C53– inherited defects in mitochondrial metabolism8E46– Reye syndrome
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DB94– Alcoholic liver diseaseDB95– Drug-induced or toxic liver diseaseJA65.0– Acute fatty liver of pregnancyME10.1– Unspecified jaundice01– Certain infectious or parasitic diseases02– Neoplasms05– Endocrine, nutritional or metabolic diseases06– Mental, behavioural or neurodevelopmental disorders18– Complications of pregnancy, childbirth and the puerperium22– Injury, poisoning or certain other consequences of external causes
Sibling codes
Foundation entity
Non-alcoholic steatohepatitis – http://id.who.int/icd/entity/1884917970
Allowed postcoordination axes
Part of: DB92: Non-alcoholic fatty liver disease › 13: Diseases of the digestive system