2A83.4

ICD-11 MMS 2026-01

Plasma cell leukaemia

Description

An aggressive plasma cell neoplasm. It is characterised by the presence of neoplastic plasma cells in the peripheral blood (PB). The neoplastic plasma cells comprise more than 20% of the white cells in the PB or the number of clonal plasma cells in the PB exceeds 2x10⁹/L.

Index terms

  • Plasma cell leukaemia
  • leukemic plasma cell
  • plasma cell leukaemia without mention of remission
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  • plasma cell leukaemia, NOS
  • plasmacytic leukaemia
  • Plasma cell leukaemia in complete remission

Exclusions from above levels

  • 2E03 – Malignant neoplasm metastasis in bone or bone marrow
  • http://id.who.int/icd/entity/501778925 – Malignant neoplasm metastasis in lymph nodes
  • http://id.who.int/icd/entity/97145147 – Malignant neoplasm metastasis in thymus gland

Sibling codes

  • 2A83.0 – Monoclonal gammopathy of undetermined significance
  • 2A83.1 – Plasma cell myeloma
  • 2A83.2 – Solitary plasmacytoma
  • 2A83.3 – Extraosseous plasmacytoma
  • 2A83.5 – Monoclonal immunoglobulin deposition disease
  • 2A83.Y – Other specified plasma cell neoplasms
  • 2A83.Z – Plasma cell neoplasm, unspecified

Foundation entity

Plasma cell leukaemia – http://id.who.int/icd/entity/2048216430

Allowed postcoordination axes

Part of: 2A83: Plasma cell neoplasms › 02: Neoplasms