Hereditary factor VIII deficiency with anti-factor VIII inhibitor

Description

A disease caused by a genetically inherited mutation leading to a deficiency in clotting due to lack of factor VIII. This disease also causes anti-factor VIII inhibitor antibodies to be produced when receiving transfusions. Anti-factor VIII inhibitor antibodies develop as the body recognises the factor VIII as foreign, therefore deeming factor VIII infusions ineffective. This disease is characterised by increasing haemorrhaging and bruising. Confirmation is by identification of mutations by genetic testing.

Index terms

Hereditary factor VIII deficiency with anti-factor VIII inhibitor

Exclusions from above levels

JA43.3 – Postpartum coagulation defects
04 – Diseases of the immune system
05 – Endocrine, nutritional or metabolic diseases

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18 – Complications of pregnancy, childbirth or the puerperium
19 – Certain conditions originating in the perinatal period
20 – Congenital malformations, deformations or chromosomal abnormalities
22 – Injury, poisoning or certain other consequences of external causes
http://id.who.int/icd/entity/1000704511 – Human immunodeficiency virus disease
JB64.1 – Other diseases of the blood or blood-forming organs or certain disorders involving the immune mechanism complicating pregnancy, childbirth or the puerperium

Sibling codes

3B10.0 – Haemophilia A
3B10.Y – Other specified hereditary factor VIII deficiency
3B10.Z – Hereditary factor VIII deficiency, unspecified

Foundation entity

Hereditary factor VIII deficiency with anti-factor VIII inhibitor – http://id.who.int/icd/entity/765707742

Part of: 3B10: Hereditary factor VIII deficiency › 03: Diseases of the blood or blood-forming organs