Central precocious puberty

Description

Central precocious puberty is defined as the onset of pubertal changes before 8 years of age in girls and before 9.5 years of age in boys due to the overproduction of gonadotropin-releasing hormone (GnRH) by the hypothalamus. It may be idiopathic with no apparent cause (90% of cases in girls, 50% of cases in boys) or secondary to a lesion (tumour or malformation) in the hypothalamus. Other causes may include traumatic brain injury, or genetic disorders, affecting behavioural and psychological development, and final body height.

Index terms

Central precocious puberty
Gonadotropin-dependant precocious puberty

Exclusions from above levels

2F7A.0 – Multiple endocrine neoplasia type 4
5A02.Y – overproduction of thyroid-stimulating hormone
5A70 – Cushing syndrome

Show allHide

5A70.0 – overproduction of pituitary ACTH
5A70.3 – Nelson syndrome
18 – Pregnancy, childbirth or the puerperium
http://id.who.int/icd/entity/1004987305 – Transitory endocrine or metabolic disorders specific to fetus or newborn

Sibling codes

5A60.0 – Acromegaly or pituitary gigantism
5A60.1 – Hyperprolactinaemia
5A60.2 – Syndrome of inappropriate secretion of antidiuretic hormone
5A60.Y – Other specified hyperfunction of pituitary gland
5A60.Z – Hyperfunction of pituitary gland, unspecified

Foundation entity

Central precocious puberty – http://id.who.int/icd/entity/1749914533

Part of: 5A60: Hyperfunction of pituitary gland › 05: Endocrine, nutritional or metabolic diseases