6C43.1

ICD-11 MMS 2026-01

Harmful pattern of use of opioids

Description

A pattern of use of opioids that has caused damage to a person’s physical or mental health or has resulted in behaviour leading to harm to the health of others. The pattern of opioid use is evident over a period of at least 12 months if substance use is episodic or at least one month if use is continuous (i.e., daily or almost daily). Harm to health of the individual occurs due to one or more of the following: (1) behaviour related to intoxication; (2) direct or secondary toxic effects on body organs and systems; or (3) a harmful route of administration. Harm to health of others includes any form of physical harm, including trauma, or mental disorder that is directly attributable to behaviour related to opioid intoxication on the part of the person to whom the diagnosis of Harmful pattern of use of opioids applies.

Excludes

  • 6C43.0 – Episode of harmful use of opioids
  • 6C43.2 – Opioid dependence

Exclusions from above levels

  • QE11.0 – Hazardous use of opioids
  • QE62 – Uncomplicated bereavement
  • QE84 – Acute stress reaction

Child codes

  • 6C43.10 – Harmful pattern of use of opioids, episodic
  • 6C43.11 – Harmful pattern of use of opioids, continuous
  • 6C43.1Z – Harmful pattern of use of opioids, unspecified

Sibling codes

  • 6C43.0 – Episode of harmful use of opioids
  • 6C43.2 – Opioid dependence
  • 6C43.3 – Opioid intoxication
  • 6C43.4 – Opioid withdrawal
  • 6C43.5 – Opioid-induced delirium
  • 6C43.6 – Opioid-induced psychotic disorder
  • 6C43.7 – Certain specified opioid-induced mental or behavioural disorders
  • 6C43.Y – Other specified disorders due to use of opioids
  • 6C43.Z – Disorders due to use of opioids, unspecified

Foundation entity

Harmful pattern of use of opioids – http://id.who.int/icd/entity/912365674

Allowed postcoordination axes

Part of: 6C43: Disorders due to use of opioids › 06: Mental, behavioural or neurodevelopmental disorders