6C43.6

ICD-11 MMS 2026-01

Opioid-induced psychotic disorder

Description

Opioid-induced psychotic disorder is characterised by psychotic symptoms (e.g. delusions, hallucinations, disorganised thinking, grossly disorganised behaviour) that develop during or soon after intoxication with or withdrawal from opioids. The intensity or duration of the symptoms is substantially in excess of psychotic-like disturbances of perception, cognition, or behaviour that are characteristic of Opioid intoxication or Opioid withdrawal. The amount and duration of opioid use must be capable of producing psychotic symptoms. The symptoms are not better explained by a primary mental disorder (e.g. Schizophrenia, a Mood disorder with psychotic symptoms), as might be the case if the psychotic symptoms preceded the onset of the opioid use, if the symptoms persist for a substantial period of time after cessation of the opioid use or withdrawal, or if there is other evidence of a pre-existing primary mental disorder with psychotic symptoms (e.g. a history of prior episodes not associated with opioid use).

Index terms

  • Opioid-induced psychotic disorder
  • psychotic disorder due to opioid intoxication

Exclusions from above levels

  • QE11.0 – Hazardous use of opioids
  • QE62 – Uncomplicated bereavement
  • QE84 – Acute stress reaction

Sibling codes

  • 6C43.0 – Episode of harmful use of opioids
  • 6C43.1 – Harmful pattern of use of opioids
  • 6C43.2 – Opioid dependence
  • 6C43.3 – Opioid intoxication
  • 6C43.4 – Opioid withdrawal
  • 6C43.5 – Opioid-induced delirium
  • 6C43.7 – Certain specified opioid-induced mental or behavioural disorders
  • 6C43.Y – Other specified disorders due to use of opioids
  • 6C43.Z – Disorders due to use of opioids, unspecified

Foundation entity

Opioid-induced psychotic disorder – http://id.who.int/icd/entity/824335105

Allowed postcoordination axes

Part of: 6C43: Disorders due to use of opioids › 06: Mental, behavioural or neurodevelopmental disorders