6C46.2

ICD-11 MMS 2026-01

Stimulant dependence including amphetamines, methamphetamine or methcathinone

Description

Stimulant dependence including amphetamines, methamphetamine or methcathinone but excluding cocaine and synthetic cathinones is a disorder of regulation of stimulant use arising from repeated or continuous use of stimulants. The characteristic feature is a strong internal drive to use stimulants, which is manifested by impaired ability to control use, increasing priority given to use over other activities and persistence of use despite harm or negative consequences. These experiences are often accompanied by a subjective sensation of urge or craving to use stimulants. Physiological features of dependence may also be present, including tolerance to the effects of stimulants, withdrawal symptoms following cessation or reduction in use of stimulants, or repeated use of stimulants or pharmacologically similar substances to prevent or alleviate withdrawal symptoms. The features of dependence are usually evident over a period of at least 12 months but the diagnosis may be made if stimulant use is continuous (daily or almost daily) for at least 3 months.

Excludes

  • 6C45.2 – Cocaine dependence
  • 6C46.0 – Episode of harmful use of stimulants including amphetamines, methamphetamine or methcathinone
  • 6C46.1 – Harmful pattern of use of stimulants including amphetamines, methamphetamine or methcathinone
  • 6C47.2 – Synthetic cathinone dependence

Exclusions from above levels

  • 6C45 – Disorders due to use of cocaine
  • 6C47 – Disorders due to use of synthetic cathinones
  • 6C48 – Disorders due to use of caffeine
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  • QE11.4 – Hazardous use of stimulants including amphetamines or methamphetamine
  • QE62 – Uncomplicated bereavement
  • QE84 – Acute stress reaction

Child codes

  • 6C46.20 – Stimulant dependence including amphetamines, methamphetamine or methcathinone, current use
  • 6C46.21 – Stimulant dependence including amphetamines, methamphetamine or methcathinone, early full remission
  • 6C46.22 – Stimulant dependence including amphetamines, methamphetamine or methcathinone, sustained partial remission
  • 6C46.23 – Stimulant dependence including amphetamines, methamphetamine or methcathinone, sustained full remission
  • 6C46.2Z – Stimulant dependence including amphetamines, methamphetamine or methcathinone, unspecified

Sibling codes

  • 6C46.0 – Episode of harmful use of stimulants including amphetamines, methamphetamine or methcathinone
  • 6C46.1 – Harmful pattern of use of stimulants including amphetamines, methamphetamine or methcathinone
  • 6C46.3 – Stimulant intoxication including amphetamines, methamphetamine or methcathinone
  • 6C46.4 – Stimulant withdrawal including amphetamines, methamphetamine or methcathinone
  • 6C46.5 – Stimulant-induced delirium including amphetamines, methamphetamine or methcathinone
  • 6C46.6 – Stimulant-induced psychotic disorder including amphetamines, methamphetamine or methcathinone
  • 6C46.7 – Certain specified stimulant-induced mental or behavioural disorders including amphetamines, methamphetamine or methcathinone
  • 6C46.Y – Other specified disorders due to use of stimulants including amphetamines, methamphetamine or methcathinone
  • 6C46.Z – Disorders due to use of stimulants including amphetamines, methamphetamine or methcathinone, unspecified

Foundation entity

Stimulant dependence including amphetamines, methamphetamine or methcathinone – http://id.who.int/icd/entity/2016549355

Allowed postcoordination axes

Part of: 6C46: Disorders due to use of stimulants including amphetamines, methamphetamine or methcathinone › 06: Mental, behavioural or neurodevelopmental disorders