6C48

ICD-11 MMS 2026-01

Disorders due to use of caffeine

Description

Disorders due to use of caffeine are characterised by the pattern and consequences of caffeine use. Caffeine is a mild psychostimulant and diuretic that is found in the beans of the coffee plant (Coffea species) and is a constituent of coffee, cola drinks, chocolate, a range of proprietary 'energy drinks' and weight-loss aids. It is the most commonly used psychoactive substance worldwide and several clinical conditions related to its use are described, although severe disorders are comparatively rare considering its ubiquity. Caffeine Intoxication related to consumption of relatively higher doses (i.e., > 1 g per day) is described. Caffeine Withdrawal is common upon cessation of use among individuals who have used caffeine for a prolonged period or in large amounts. Caffeine-Induced Anxiety Disorder has been described, often following intoxication or heavy use.

Excludes

  • 6C46 – Disorders due to use of stimulants including amphetamines, methamphetamine or methcathinone
  • QE11.5 – Hazardous use of caffeine

Exclusions from above levels

  • QE62 – Uncomplicated bereavement
  • QE84 – Acute stress reaction

Child codes

  • 6C48.0 – Episode of harmful use of caffeine
  • 6C48.1 – Harmful pattern of use of caffeine
  • 6C48.2 – Caffeine intoxication
  • 6C48.3 – Caffeine withdrawal
  • 6C48.4 – Certain specified caffeine-induced mental or behavioural disorders
  • 6C48.Y – Other specified disorders due to use of caffeine
  • 6C48.Z – Disorders due to use of caffeine, unspecified

Sibling codes

  • 6C40 – Disorders due to use of alcohol
  • 6C41 – Disorders due to use of cannabis
  • 6C42 – Disorders due to use of synthetic cannabinoids
  • 6C43 – Disorders due to use of opioids
  • 6C44 – Disorders due to use of sedatives, hypnotics or anxiolytics
  • 6C45 – Disorders due to use of cocaine
  • 6C46 – Disorders due to use of stimulants including amphetamines, methamphetamine or methcathinone
  • 6C47 – Disorders due to use of synthetic cathinones
  • 6C49 – Disorders due to use of hallucinogens
  • 6C4A – Disorders due to use of nicotine
  • 6C4B – Disorders due to use of volatile inhalants
  • 6C4C – Disorders due to use of methylene-dioxymethamphetamine [MDMA] or related drugs, including methylene-dioxyamphetamine [MDA]
  • 6C4D – Disorders due to use of dissociative drugs including ketamine or phencyclidine (PCP)
  • 6C4E – Disorders due to use of other specified psychoactive substances, including medications
  • 6C4F – Disorders due to use of multiple specified psychoactive substances, including medications
  • 6C4G – Disorders due to use of unknown or unspecified psychoactive substances
  • 6C4H – Disorders due to use of non-psychoactive substances
  • 6C4Y – Other specified disorders due to substance use
  • 6C4Z – Disorders due to substance use, unspecified

Foundation entity

Disorders due to use of caffeine – http://id.who.int/icd/entity/31898480

Allowed postcoordination axes

Part of: 06: Mental, behavioural or neurodevelopmental disorders